Age related loss of muscle mass and function can lead to lifestyle as well as socio-economic and public health challenges. A recent study from Denmark looked compared individuals at least 83 years of age who trained with weights three times weekly to those who did not, and found that weight training led to an improvement in muscle bulk and strength. The take home point here is that you’re never too old to benefit from exercise and a healthier lifestyle.
Investigators from NYU published a study in this week’s New England Journal of Medicine involving over 9500 individuals with coronary heart disease, showing that body weight variability increases the risk of stroke, heart attack, and death. These data are consistent with other data in healthy adults showing that weight cycling can lead to increases in cardiovascular and cancer deaths. The take home point is that yo-yo dieting is not good for your health.
A recent report in the International Journal of Cancer looked at lifestyle information for 142,239 men participating in the European Prospective Investigation into Cancer and Nutrition. Over an average follow up of 14 years, there appeared to be a small but significant reduction in the risk of a prostate cancer diagnosis among the men with the highest fruit intake, particularly citrus fruit. A similar effect with vegetable intake could not be identified. Although higher fruit intake appeared to reduce the risk of being diagnosed with prostate cancer, it did not appear to reduce the risk of dying from prostate cancer.
A recent study from the journal Breast Cancer Research has looked at over 57,000 women who participated in the California Teachers Study from 1995-2005, and has concluded that women who took low dose aspirin at least three times weekly had a 16% reduction in the risk of breast cancer.
In a recent meta-analysis published in the British Medical Journal, investigators from the University of Montreal reviewed 8 studies, comprising nearly 450,000 patients, connecting the use of common non-steroidal anti-inflammatory agents (NSAIDs) like ibuprofen (Motrin) or naproxen (Aleve) with heart attacks. Overall, they found that use of NSAIDs at any dose for at least a week increased the risk of heart attack 20-50% compared to those who had not used these medications. The risk appeared greatest during the first month of use, particularly if taking high doses of drug. Drilling down to the individual medications, they reported a possible 75% increased risk among users of ibuprofen and naproxen. Because of the size of their study, the investigators state that they can conclude with 90% certainty that NSAID use increases the risk of heart attacks.